Description
This vial contains Sema, a synthetic analogue of Glucagon-Like Peptide-1 (GLP-1). This peptide is frequently utilized in research settings to investigate glucose homeostasis, insulin secretion pathways, and metabolic regulation.
Chemical Profile
This product is a high-purity (>99%), lyophilized (freeze-dried) powder requiring reconstitution. It is intended for laboratory handling and experimental analysis only.
Component: Sema (GLP-1 Analogue)
Total Quantity: [5mg]
Purity: >99% (Determined by HPLC)
Quality Assurance
HPLC Analysis: Validated >99% purity.
Mass Spectrometry: Confirmed molecular weight and structure.
Toxicity: Not tested for human safety.
Research Context (Literature Review)
Note: The following is for educational purposes regarding the chemical properties of these peptides and does not constitute a medical claim.
Semaglutide shares 94% structural homology with native human GLP-1 but has been modified to resist degradation by the DPP-4 enzyme. In laboratory studies, it acts as a selective agonist for the GLP-1 receptor.
Research indicates that binding to this receptor stimulates insulin secretion in a glucose-dependent manner and inhibits glucagon secretion. Additionally, animal models have shown that Semaglutide influences gastric emptying rates and signals satiety centers in the hypothalamus, making it a key compound in the study of metabolic syndrome and obesity-related pathways.
Technical Specifications
| Specification | Data |
| CAS Number | 910463-68-2 |
| Molecular Formula | $C_{187}H_{291}N_{45}O_{59}$ |
| Molecular Mass | 4113.58 g/mol |
| Appearance | White to off-white lyophilized powder |
| Solubility | Soluble in Bacteriostatic Water or Sterile Water |
| Storage (Lyophilized) | Store at -20°C (Freezer). Stable for up to 24 months. |
| Storage (Reconstituted) | Store at +4°C (Refrigerator). Use within 4 weeks. |






